IPHL Services and Capabilities

Industrial Pharmacy Lab

Specializing in comprehensive preclinical development, IPHL has the ability to take clients across the entire lifecycle of a drug candidate—from discovery, PK/PD modeling, and analytical support to preformulation and formulation.

All IPHL services are completed in a GLP-compliant environment.

IPHL also offers hands-on training and certification courses in several areas of drug development.   

Our capabilities include, but are not limited to:

Analytical method development and validation

  • UV, fluorescence, and circular dichroism spectroscopy
  • HPLC, LCMS
  • ELISA, cell-based biological assays
  • Stability studies

Characterization

  • Particle size
  • Morphology and polymorphism
  • Thermal analysis

Preformulation studies

  • Excipient compatibility
  • Solubility screening
  • Hot-melt feasibility
  • Particle size reduction
  • Lyophilization cycle development

Formulation development

  • Oral solid dosage forms
  • Ophthalmic delivery
  • Parenteral drug delivery systems
  • Lipid based systems, nano-microsphere, and disperse systems
  • Protein formulations

Bioavailability and comparator studies

Full pharmacokinetic profile of new drug candidates

  • ADME studies in several animal species, metabolic profile using metabolomics software
  • Animal studies in a fully staffed AAALAC-accredited vivarium facility on campus
  • Bioanalytical support

Contact:

Dr. Pardeep Gupta
Director, Industrial Pharmacy Lab

Address:

Pharmacology and Toxicology Center, Room 243

Phone:

215-895-1141

Email:

iphl@usciences.edu