University of the Sciences in Philadelphia

Charalampos (Babis) Papachristou, PhD

Education:

PhD, Statistical Genetics, Ohio State University
BS, Mathematics, The Aristotle University of Thessaloniki in Greece

Prior Positions:

•  Postdoctoral Fellow, Department of Human Genetics, University of Chicago, 2005-2007

Teaching Responsibilities:

• ST310 Introduction to Biostatistics

• ST321 Advanced Topics in Probability

• ST336/ST736 Survival Analysis

• ST340/ST711 SAS Programming and Data Analysis

• ST710 Biostatistical Methods
  

Research Interests:

Statistical Genetics: Genetic studies involve analysis of marker (landmarks on the genome) data from families (pedigrees) with multiple affected individuals.  The large volume of data generated by such studies as well as the comlex dependencies in these data pose many interesting and challenging research questions.  Dr. Papachristou's work specifically aims at addressing some of these problems.  In particiular, he is intereseted in developing novel methodologies for indentifying, with high confidence, chromosomal regions that harbor disease susceptibility genes (loci). 

Publications:

Vas, L., Papachristou, C., (2010) "A Note on (α, β )-higher Derivations and their Extensions to Modules of Quotients", Ring and Module Theory - Trends in Mathematics, Birkhauser Verlag Basel, Switzerland, 165-174.

Biswas, S., Papachristou, C., (2010) "Accounting for Disease Model Uncertainty in Mapping Heterogeneous Traits - A Bayesian Model Averaging Approach", Human Heredity 69:242-253

Papachristou, C., Abney, M., Lin, S. (2007) "Confidence intervals for putative quantitative trait loci - development and applications of new linkage methods", BMC Proc. 1(Suppl 1): S91.

Papachristou, C. and Lin, S. (2006c) "Comparison of methods for constructing confidence intervals for the location of putative trait loci", Genetic Epidemiology 30:677-689.

Papachristou, C. and Lin, S. (2006a) "Microsatellites versus single-nucleotide polymorphisms in confidence interval estimation of disease loci", Genetic Epidemiology 30:3-17.

Papachristou, C. and Lin, S. (2006b) "A two step procedure for the construction of confidence regions for putative trait loci with application to data from families with multiple cases of Rheumatoid Arthritis", Genetic Epidemiology 30:18-29./p>

Papachristou, C. and Lin, S. (2005). "A confidence set inference procedure for gene mapping using markers with incomplete polymorphism", Human Heredity, 59:1-13.

Papachristou, C. and Lin, S. (2005) "Interval estimation of disease loci - Development and applications of new linkage methods", BMC Genetics, 6(Suppl 1):S21

Biswas, S., Papachristou, C., Irwin, M. and Lin, S. (2003). "Linkage analysis of the simulated data – Evaluations and comparisons of methods", BMC Genetics, 4:S70.